“...whether they took treaty or not, they were subject to the laws of the Dominion.”

Do Not Ask Whether They Have a Cognitive Map, but How They Find Their Way About

The publication of "The hippocampus as a cognitive map" (O'Keefe & Nadel, 1978) has had a remarkable impact, stimulating a huge amount of both behavioural and neurobiological research on spatial learning and memory, involving both laboratory and field studies, and employing a variety of novel techniques. The reviews of this general area of research provided by the previous contributors to this ...

Proteomics in asthma: the clinicians were right after all, were not they?

Clinical disease phenotypes with underlying information of molecular and biological signatures for the same, is a prerequisite for improving medical care and developing more effective, stratified management strategies. This commentary reviews the research carried out by Cao et al. to unravel biological networks associated with different clinical categories of asthma. It finally comments on the ...

Geriatrics: in our residents' future whether they know it and like it or not.

The American population—and, indeed, the world’s population— is getting older. Worldwide, over the next 40 years, the number of the people over 60 is expected to increase threefold to reach nearly 2 billion. One in every five people on the planet will be 60 years or older, and one in six will be least 65 years old.1 The situation is similar in the United States, where the number of people over ...

Higher Plant Proteins of Cyanobacterial Origin: Are They or Are They Not Preferentially Targeted to Chloroplasts?

Dear Editor, What does the evolutionary origin of a plant protein tell about its subcellular localization? Naively thinking, one would assume that plant proteins that were originally encoded in the endosymbiont genome are targeted to the chloroplast. However, published data seem to support only a loose link between evolutionary origin and subcellular localization. About half of the Arabidopsis ...

Ready or not, here they come.